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University Press Scholarship Online
Oxford Scholarship Online
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The Neurobiology of an Insect Brain

Malcolm Burrows

Print publication date: 1996

Print ISBN-13: 9780198523444

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9780198523444.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (www.oxfordscholarship.com). (c) Copyright Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a monograph in OSO for personal use (for details see http://www.oxfordscholarship.com/page/privacy-policy ).date: 08 July 2018

DOI:10.1093/acprof:oso/9780198523444.003.0005

A neurotransmitter is a messenger released from a neuron at an anatomically specialised junction, which diffuses across a narrow cleft to affect one or sometimes two postsynaptic neurons, a muscle cell, or another effector cell. A neuromodulator is a messenger released from a neuron in the central nervous system, or in the periphery, that affects groups of neurons, or effector cells that have the appropriate receptors. It may not be released at synaptic sites, it often acts through second messengers and can produce long-lasting effects. The release may be local so that only nearby neurons or effectors are influenced, or may be more widespread, which means that the distinction with a neurohormone can become very blurred. A neurohormone is a messenger that is released by neurons into the haemolymph and which may therefore exert its effects on distant peripheral targets. It may differ only in degree from a neuromodulator in the extent of its action.

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At Kickstarter's Ghost Arcade if anyone wants to come play! pic.twitter.com/Q1lFGnOnS8

— Kingdom Death (@kingdomdeath) October 29, 2016

4. Kingdom Death: Monster 1.5 – $12,393,139

This cooperative tabletop game is Dungeons Dragons meets The Sims, where players create characters, craft weapons and gear, and fight monsters – while also building a civilization in between creature battles. The first version was released in 2015, but this upgrade due out in 2020 raised $1 million within 19 minutes of going live last fall.

3. Pebble 2, Time 2 – $12,779,843

These updates to the Pebble and Pebble Time watchers are another bittersweet success story. After pulling almost $13 million from more than 66,000 Kickstarter supporters last year, Pebble announced in the fall that it would refund backers and no longer manufacture or support its devices, nor honor existing warranties.

Hey Coolest people! Submit your fav Coolest Cooler pics for a chance to be shared w/ the rest of the Coolest family. Here's a few we love: pic.twitter.com/4aZkYX4FiS

— The Coolest Cooler (@Coolest_Cooler) October 17, 2016

2. Coolest Cooler – $13,285,226

This icebox – then marketed for $299 – considers itself the “coolest” thanks to a built-in ice crushing blender to whip up margaritas and smoothies, besides just keeping drinks and tailgate treats cold. It also boasts a waterproof Bluetooth speaker to play tunes, and a built-in USB charger to keep your devices juiced up. They now run in four colors for $449 .

1. Pebble Time – $20,338,986

The 2015 Pebble Time remains the most-funded Kickstarter project so far, even as Pebble itself has ceased production of smartwatches and was acquired by Fitbit in late 2016. But it was a great run. Pebble shipped more than 2 million Pebbles around the world.

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